International Journal of Public Health, Pharmacy and Pharmacology (IJPHPP)

EA Journals

kidney injury

Kidney-Induced Injury from Native Herbal Drugs: A Case Study of Certain Herbs Used in the Management of Infertility in Calabar, Nigeria (Published)

Infertility is a global concern among married couples. Severally treatment approaches have been used over the years to proffer solution. This research aims at investigating the kidney–induced injury from native herbal drugs-case study of certain herbs used in the management of infertility in Calabar. A total of 18 Wistar rats weighing 150 – 250 grams were separated into 3 groups of 6 rats each and 2 groups were administered with 200 mg/kg each of ethanol and n-hexane combined extracts for 7 days. Results showed that ethanol and n-hexane extracts groups significantly affected the renal tissues of the experimental animals. While in control group, a section of the kidney showed normal findings of glomeruli and renal tubules. The ethanol extract group showed swollen glomeruli with deeply stained mesangial cells while the n-hexane extract group showed the glomeruli had a hypocellular mesangium causing a peri-arteriolar mesangial haemorrhage. Ethanol extract group and n-hexane extract group showed injury to the renal tissues on histology.

Keywords: Infertility, herbal extracts, kidney injury

Scroll to Top

Don't miss any Call For Paper update from EA Journals

Fill up the form below and get notified everytime we call for new submissions for our journals.