Global Journal of Pure and Applied Chemistry Research (GJPACR)

EA Journals

4-Amino Antipyrine

Preparation, Characterization and Study the Biological Activity of New No2, Novel N2o2 Ligands and Their Complexes with [Co (Ii), Cu (Ii), Ni (Ii), Mn (Ii) and Hg (Ii)] Ions (Published)

A new two Schiff bases derivatives was synthesized and characterized with studying their biological activity and employed anganese (II),Cobalt (II),Nickel(II),Copper(II) and Mercury (II) complexes: 2 – ((Z) – 4 – ((Z)-2-hydroxy-1, 2-diphenylethylideneamino)-1, 5 – dimethyl – 2-phenyl-1H-pyrazol-3(2H)-ylideneamino) benzoicacid and (E)-4-(2-hydroxy-1, 2-diphenylethylideneamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one. The first ligand were obtained through a reaction of Benzoin and 4-Aminoantipyrine while the second result from the condensation of the first ligand with 2-amino benzoic acid. Ten new coordination compounds were synthesized and structurally characterized: [Co(L1)(Cl)], [Cu(L1)(Cl)] [Ni(L1)(Cl)],[Mn(L1)(Cl)],[Hg(L1)(Cl)],[Co(L2)],[Ni(L2)],[Cu(L2)], [Mn(L2)] and [Hg (L2)]. All of the suggested chemical structures of the prepared ligands and metal complexes are confirmed by using FT- IR, UV, 1H& 13C-NMR spectra. Most of the prepared compounds show antibacterial activity to (Staphylococcus aureus), (Escherichia coli), (Bacillus subtilis) and (Pseudomonas aeroginosa).

Keywords: 2-Aminobenzoicacid, 4-Amino Antipyrine, Benzoin, Biological Activity, Characterization, Schiff Bases

Scroll to Top

Don't miss any Call For Paper update from EA Journals

Fill up the form below and get notified everytime we call for new submissions for our journals.