Forty cases of women sever from recurrent pregnancy loss (RPL) compared with 40 normal women for determining the cytokine gene polymorphism in the promoter region of : tumor necrosis factor-alpha TNF-α (-308 G/A), interleukin IL-6 (-634 G/C) and IL-10 (-592 C/A) in aborted women of Basra /Iraq. The results indicated that there was an association between RPL and the polymorphisms in inflammatory cytokines (IL-6, TNF-α), while IL-10 gene did not showed any effect on both cases of RPL and normal cases.
Keywords: Cytokine Genes, IL-10, IL-6, Loss, Recurrent Pregnancy, TNF-α