The proteolytic activation is an important event in the cycle of viral infection [1]. In cases of interfering into any stage of this cycle the parental viruses, virions, can give rise to numerous progeny that will possess no infecting properties as its structure does not contain active fusion proteins to ensure virus penetration into a healthy cell. Therefore, proteolytic activation determines the virulence of viruses and their ability to produce infection. Apparently, the viral ability to infect certain tissues of the body is predetermined by the presence in organs and tissues of enzymes required to provide proteolytic activation for viral progeny [2]. Nowadays proteolytic enzymes are provoking interest in almost all the fields of medicine. Moreover, there have been a number of diseases which pathogenesis involves proteinases. The purpose of this study was to secure trypsin-like protease from the lungs of healthy mice and to obtain hyperimmune serum derived from their plasma for treating simulated influenza. Lungs taken from 100 white mice were used to isolate trypsin-like protease. Virus A / PR / 8/34 was used to induce influenza. White rats were used to prepare hyperimmune anti-proteinase sera in order to study their protective function on white mice infected with a lethal dose of influenza a.
Keywords: genetic education, premarital genetic screening, religious institutions, would-be partners
