Antirpoteinase Vaccines in Modeling Influenza Virus Infection (Published)
The proteolytic activation is an important event in the cycle of viral infection [1]. In cases of interfering into any stage of this cycle the parental viruses, virions, can give rise to numerous progeny that will possess no infecting properties as its structure does not contain active fusion proteins to ensure virus penetration into a healthy cell. Therefore, proteolytic activation determines the virulence of viruses and their ability to produce infection. Apparently, the viral ability to infect certain tissues of the body is predetermined by the presence in organs and tissues of enzymes required to provide proteolytic activation for viral progeny [2]. Nowadays proteolytic enzymes are provoking interest in almost all the fields of medicine. Moreover, there have been a number of diseases which pathogenesis involves proteinases. The purpose of this study was to secure trypsin-like protease from the lungs of healthy mice and to obtain hyperimmune serum derived from their plasma for treating simulated influenza. Lungs taken from 100 white mice were used to isolate trypsin-like protease. Virus A / PR / 8/34 was used to induce influenza. White rats were used to prepare hyperimmune anti-proteinase sera in order to study their protective function on white mice infected with a lethal dose of influenza a.
Keywords: genetic education, premarital genetic screening, religious institutions, would-be partners
Effect of Genetic Education on Knowledge of Would-Be Partners towards Premarital Genetic Screening Uptake in Selected Religious Institutions in Yenagoa, Bayesa State, Nigeria (Published)
Premarital screening presents an opportunity for individuals to become informed about their genetic predisposition to diseases. This study assesses the effect of genetic education on knowledge of would-be partners towards premarital genetic screening uptake in selected religious institutions in Yenagoa, Bayelsa State. A quasi experimental of pretest/post-test research design was adopted and 109 respondents were randomly selected. A self-administered questionnaire was used to elicit information from respondents at both pre- and post-seminar. Analysis was done using descriptive and inferential statistics on Statistical Package for Social Sciences (SPSS) version 23 at 0.05 level of significance. Findings revealed that majority have heard of premarital genetic screening and were aware of the diseases meant for screening. Only 26.6% have ever gone for any premarital genetic screening. Overall, 40.4% and 88.1% had good uptake of premarital genetic screening before and after the seminar. Significant relationship exists between knowledge of premarital genetic screening in pre and post-seminar and between premarital genetic screening and the uptake (p < 0.05). Therefore, genetic education should be intensified for wolud-be partners in religious institutions.
Citation: Mary Idowu Edward, Mercy Olawumi Akinro, Oyekunbi Adebimpe Fatile and Alice Odunlayo Ayelabola (2022) Effect of Genetic Education on Knowledge of Would-Be Partners towards Premarital Genetic Screening Uptake in Selected Religious Institutions in Yenagoa, Bayesa State, Nigeria, International Journal of Micro Biology, Genetics and Monocular Biology Research, Vol.6, No.1, pp.10-28
Keywords: genetic education, premarital genetic screening, religious institutions, would-be partners