This research work was carried out to investigate the knowledge of laboratory health practices possessed by senior secondary school students in the North-Central geopolitical zone of Nigeria. A total of 893 students were sampled in North-Central Nigeria by means of stratified random sampling using the Questionnaire as an instrument. Data acquired was analysed using comparison of means and t-test at 0.05 statistical level of significance. The result of the study showed that the knowledge of laboratory precautionary practices possessed by the students is fairly good. In terms of gender, school type and location: Female students expressed a better knowledge than their male counterparts, Also, students from private and urban schools performed significantly better than their counterparts in the public and rural schools respectively. The researchers recommended that Science teachers should emphasize familiarity and understanding of laboratory warning symbols among others.
Keywords: Hazard Symbols, Health Practices, Knowledge, Laboratory, north Central