This study aims to assess the impact of a nurse-led interactive education on the perception of COVID-19 vaccine safety among nurses at Lagos State University Teaching Hospital (LASUTH) in Lagos, Nigeria. Utilizing a quasi-experimental, pre-/post-test one-group design, the study involved 527 nurses at LASUTH. The sample size of 250 was determined using the Yamane formula. Data was collected through a questionnaire with demographic and perception sections. Face and content validity were established, and a pilot study demonstrated instrument reliability (Cronbach alpha = 0.88). Participants were informed, and consent was obtained before administering pre-test questionnaires. Following the pre-test, a nurse-led interactive education session on COVID-19 vaccine safety occurred. Post-test questionnaires were distributed after the session. Statistical Package for the Social Sciences (SPSS) version 25 was employed for data analysis using descriptive and inferential statistics (independent sample t-test). The results, revealed a significant difference in COVID-19 vaccine safety perceptions among nurses pre- and post-intervention (p < 0.05). The pre-intervention mean score (8.4±2.52) was lower than the post-intervention mean score (9.69±1.82), indicating a notable increase in safety perceptions. The analysis showed a substantial mean difference (Mean diff. = 1.29, t (235) = 24.26, p = .014), rejecting the null hypothesis. In conclusion, the nurse-led interactive education program effectively influenced nurses’ perceptions, enhancing their acceptance and confidence in COVID-19 vaccination. Recommendations include the development of comprehensive programs to address vaccine safety concerns and targeted surveys or focus group discussions to identify specific areas of concern among nurses.
Keywords: Nurse-Led Interactive Education, Nurses, Perception, Vaccine Safety
