This study investigates, the human capital development in science and technology in Nigeria. It used ordinary least regression technique and time series date from 1986-2017 which were sourced from Central Bank Statistical Bulletin. The variables were tested for unit root and co-integration they are found to have a long run relationship with RGDP. However, the result indicates that human capital development affects the administrative growth of the economy within the study period. This study therefore recommends that adequate attention must be given to the equipping of our schools with modern research facilities and technological experimentation device and government should improve conditions of service for workers in the educational sector and more competent hands that will help improve productivity of the national economy at large needs to be engaged.