The objective of this paper is to discuss issues and challenges driving entrepreneurship education in Nigeria. Since entrepreneurship education remain vital in the real sector and the sustenance of economic development, it has become necessary for Nigerian Government to pay attention to this sector. This paper, therefore, argues that entrepreneurship education will equip the unemployed youths with the skills with which to be self-reliant. Also, the paper recommended that educational programmes at all levels of education should be made relevant to provide the youths the needed entrepreneurial skills. It also recommended that the Nigerian Government should give adequate attention to full blown entrepreneurial education in Nigeria.