Global Journal of Pure and Applied Chemistry Research (GJPACR)

EA Journals

Antioxidant

Extraction of Phenolic Contents from Cucurbita Pepo (Published)

Cucurbita p. is a commonly grown vegetable plant which is widely available in Southern African and other African states inculding Nigeria. However, Cucurbita belong to cucurbitaceae family generally known as pumpkin consumed as leafy, vegetable, fruits, flowers and seeds, which can then be simply boiled and eaten. Cucurbita p. contains as many important substances as possible such include calcium, iron, vitamins, oil, and protein etc and similarly provides natural antioxidants such as vitamin A, vitamin C, vitamin E, beta carotene which slow the process of aging by preventing free radicals from oxidizing sensitive biological molecules. Folin ciocalteu reagent was used to determine the total phenolic content present in the Cucurbita p. samples. The result indicated that, the total phenolic content in Cucurbita pepo fraction with petroleum ether is 17.1mg/g of garlic acid and methanol extract with 12.6mg/g showed high phenols while ethanol fraction was the lowest phenolic content with 8.0mg/g. The analysis using HPLC chromatogram shows presence of compounds at 254nm and at different retention times. Therefore, Cucurbita p. is a source of natural antioxidant due to the antioxidant activity determined.

Keywords: Antioxidant, Cucurbita plant sample, Gallic acid solution., Lowry solutions, Phenolic contents

A Review Study of the Chemical Constituents and Therapeutic Effects of Peganum Harmala L (Published)

Peganum harmala L  was used traditionally in different populations for many medical complains. It contained a wide range of chemical constituents.. The previous studies showed that the seeds of the plant and its constituents exerted antimicrobial, anticancer, antioxidant, antidiabetic and  analgesic effects and many other pharmacological activities. Harmaline, harmine, harmalol, harman, quinazoline derivatives, vasicine, vasicinone, anthroquinons and fixed oils are reported from seeds and roots of this plant. This plant is used as a medicine in Turkey, Syria, Iran, Pakistan, India, Egypt and Spain. This article presents comprehensive analyzed information on the botanical, chemical and pharmacological aspects of P. harmala.

Keywords: Antidiabeetic, Antioxidant, Harmaline, Peganum Harmala

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