European Journal of Biology and Medical Science Research (EJBMSR)

EA Journals

Therapy-Prophylaxis

Comparing Therapeutic and Prophylactic Moderation of Perturbation of Erythrocytic and Platelet Functions in Ultraviolet Irradiated Rabbits Fed 2% Turmeric Supplement (Published)

Recent moderation of lympho-leukocyctic responses of acutely ultraviolet (UV) irradiated pre-pubertal rabbits (PR) by 2% organic turmeric (Curcuma longa) supplement raises the possibility of wider protective implications for other blood components. This study thus investigated UV effects on erythrocytic/hematologic indices (EHI) and platelet (PLT) functions in PR and compares acute and chronic effects of T thereon. The study was for 85days (d) in three (3) phased periods: 40d pre-irradiation, 5d irradiation and 40d post-irradiation in 60 acclimatized unsexed PR randomly assigned to 4 groups of 12 PR each as follows: Group 1, Control was fed un-supplemented diet and forage (Tridax procumbens) – basal diet (BD) for the entire study period without any treatment. Group 2 – T group (T+T+T) was fed BD supplemented with 2% pulverized crude T (BDS) during periods 1, 2 and 3, without irradiation. Group 3 – radiation (R) group (- +R+ -) was fed BD at periods 1, 2 and 3 and irradiated. Group 4 – therapeutic (H) group (- + R+T) was treated as in group 3 and fed BDS at period 3 only. Group 5 – prophylactic (P) group (T+TR+ -) was fed BDS during periods 1 and 2 only and irradiated. Feed and water were available ad libitum. Blood was collected on 86d from 0900h. Data were analyzed by ANOVA. UV significantly (p<0.05) suppressed RBC count, hemoglobin concentration and hematocrit as well as platelet function. BDS normalized these variables towards control values. H application of T significantly (p<0.05) elevated the variables to control values. A P application of T very significantly (p<0.05) elevated values of these variables relative to acutely treated PR. These results demonstrate that T whether applied acutely or chronically moderated, UV induced perturbation of EHI and PLT functions of these PR.

Keywords: Erythrocytic-Platelet-function, Rabbits, Therapy-Prophylaxis, Turmeric, Ultraviolet radiation

Scroll to Top

Don't miss any Call For Paper update from EA Journals

Fill up the form below and get notified everytime we call for new submissions for our journals.