Isolation and Characterization of Phenanthrene Methyloctanoate from the Leaves of Antiaris Africana

Plants are sources of bioactive compounds which are used directly as therapeutic agents, as well as starting material for the synthesis of drugs, .Antiaris africana plant is one of such medicinal plants. It is used in the treatment of mental and nervous disorder such as epilepsy. It is also used to treat respiratory infections, syphilis and skin irritants in Nigeria. An Ester, Hexadecahydro – 3, 17 – dihydro – 5, 10, 13, 14 –   tetramethyl – 1 H- cyclopenta ( α ) phenanthren – 17 – yl, 7 – methyloctanoate  was isolated and characterized from the leaves of Antiaris africana using IR, ¹H NMR, ¹³C NMR, MS, COSY and DEPT. The presence of the isolated compound in the leaves of A. africana may be responsible for some of the biological activities exhibited by plant.

KEYWORDS: Natural Product, Ester, Antiaris Africana, Diseases

Keywords: Antiaris Africana, Diseases, Ester, Natural Product