Stachytarpheta cayennensis is a plant full of phytonutrient, it has been applied by many traditional healers to treat host of diseases. Its full constituents have not been fully documented. The phytochemical screening of the root of this plant revealed the presence of alkaloids, tannins, saponins, glycosides, steroids and phenols. The antimicrobial analysis on selected human pathogens; Streptococcus specie, Staphylococcus aureus, Klebsiella, Proteus specie and Pseudomonas specie showed that the extract was only sensitive to Proteus specie having a diameter of inhibition of 4mm at concentration of 240mg/cm3 and minimum inhibition concentration of 120mg/cm3. The spectrum obtained from the GC/MS analysis showed ten peaks at M/z 128 ,220,242,256,252,270,256, 296, 282 and 281 corresponding to molecular formulas of C10H8 for Cyclopentyl cycloheptene, C15H24 for Butylated hydroxyl toluene, C16H320 for Hexadecanoic acid, C16H28O2 for 11-tetradecyl-1-ol acetate, C17H38O2 for Hexadecanoic acid methyl ester,C16H32O2 for n-hexadecanoic acid C19H34O2 for 9-octadecenoic acid methyl ester, C18H34O2 for octadec-9-enoic acid and C18H35NO for 9-octadecenamide respectively. 9-octadecenamide (Oleamide) is useful for the treatment of insomnia. Oleamide accumulates in the cerebrospinal fluid during sleep deprivation and thus induces sleep in animals. It may be a potential medicinal treatment for mood and sleep disorders
Keywords: Human Pathogens, Phytonutrients, Stachytarpheta Cayennensis, phytochemicals