The present study explores the hypothesis of cognitive reagents for early detection of dementia and impairment in various cognitive domains. A comprehensive analysis of task-based assessments using specific cognitive tasks targeting different aspects of cognitive functioning is proposed. Ten cognitive domains, including numerical/alphabetical attention, word/image recall, comparison/differentiation, generalization, numerical reasoning, verbal reasoning, shape recognition, general quantitative reasoning, time/place orientation, and concept description, are investigated as potential biomarkers, with corresponding cognitive tasks acting as reagents for evaluating cognitive impairment. By examining the effectiveness of these cognitive reagents, the study aims to contribute to the development of reliable and efficient methods for assessing cognitive functioning and detecting early signs of dementia.
Keywords: Biomarkers, Cognitive, aging, dementia, detection, impairment, reagents
