Assessment of White Blood Cell in Abo Blood System of Blood Group Among Students: A Study in Bauchi State University Gadau Main Campus (Published)
ABO blood system relationship to infections and other pathological conditions Individuals with certain types of ABO blood groups are more susceptible to diverse kinds of infections. Blood grouping has been one of the major factors for identification of biological materials in forensic investigations and is a widely used technique in forensic laboratories. The presence of ABO blood group and Rhesus factor is applied to inherited antigens detected on red cell surface by specific antibodies. WBC count is the number of neutrophils, lymphocytes, monocytes, eosinophils, basophils, and immature or atypical cells present in 1 mL of blood, Elevation of the WBC requires accurate differential count and morphologic evaluation of the peripheral blood smear along with clinical information to determine the cause. The normal range percentage of the different types of WBCs is as follows: Neutrophils 50-70% Eosinophils 1-4% Basophils 0.4% Monocytes 2-8% Lymphocytes 20-40%A total number of 60 healthy subjects were used for the research, they comprise 16, 14, 8, 22 (A, B, AB and O) respectively with white blood cell counts and Rhesus factor were analyzed. All patients were subjected to differential white blood cell which was carried out in the laboratory. Result was statistically analyzed by Microsoft excel and SPSS. We observed that blood group O had significantly higher values of white blood cell count with p value of <0.05. White blood cell count is more significant in O+ blood group irrespective of their gender but differ in ethnicity.
Keywords: ABO blood group, Morphology, Patients, Rhesus, blood, forensic, white blood cells count
Clinical Effect of Moringa oleifera on Body mass index,Triglyceride and High density lipoprotein in Subjects Taken Tenofovir Combination Regimen (Published)
Antiretroviral drugs can have adverse effects. Most are manageable, but some can be serious. The aim of this clinical study is to evaluate the potential benefits of taking Moringa oleifera on body mass index (BMI), blood triglyceride and High density lipoprotein (HDL) level in patient taking Tenofovir/Lamivudine/efavirenz (TLE) combination. The study was designed as a Longitudinal Randomized Comparative Trial (LRCT) involving 140 HIV adult subjects (56 males, 84 females) who have been on Tenofovir/Lamivudine/efavirenz (300/300/600mg) TLE combination for at least 6 months prior to the study. They were recruited from a Teaching Hospital in Nigeria. Moringa oleifera capsules (200mg) were administered by the subjects to be used beginning from the first day of visit 0, through visit 1 (after four weeks) and 2 (after 12 weeks). Blood samples of subjects were collected at each visit (visit 0, 1 and 2) and analyzed for triglyceride and HDL level.There was no significant reduction in serum HDL level (P<0.01) of subjects in visit 1 but there was significant (P<0.01) increase on visit 2 when compared to visit 0. There was also significant improvement in blood triglyceride level (P<0.01) in visit 1 and 2 compared to visit 0 of tenofovir/Lamivudine/Efavirenz (TLE) moringa combination. Results from the study suggests that Moringa oleifera may be useful in improving triglyceride and cholesterol level of patients receiving TLE combination.
Keywords: Moringa oleifera, Tenofovir, blood, glucose, triglyceride