Citation: Iwu Irenus Chinonye; Alisa Christopher .O; Anukam Basil ; Ali Bilar ; Ezekoye Miracle Ouchukwu; Igbomezie Maryann C. ;Anozie Remigius Chukwudi; Okoro mary.U and Obiagwu Ifeoma (2022) Chemical and Medicinal Properties of Spondias Mombim (Linn) Leaf Harvested From the South Eastern Nigeria, Global Journal of Pure and Applied Chemistry Research, Vol.10, No.1, pp.1-21
Abstract: Spondia Mombin Linn is a very important medicinal plant used in the sourth eastern Nigeria for the treatment of various ailment , Initial phytochemical analysis of the leaf revealed the presence of alkaloids 2.2%, flavonoids 1.34%, saponins 3.73%, tannins 2.4%, cardiac glycosides and steroids .The antimicrobial analysis against certain selected human pathogens revealed activities against Staphylococus aureus by a diameter of 35mm, Streptococcus specie 30mm ,Aspergillis niger 18mm and Mucor specie 19mm but could not inhibit the growth of Klebsiella specie and Pseudomonas aeruginosa .GC-MS of the chloroform extract was carried out with SHIMAZU Japan Gas Chromatography 5890-11 with a fused GC column OV 101coated with polymethyl silicon (0.25 mm x 50 m) and Gas chromatography Mass spectrum GC-MS QP 2010 Plus Shimazu Japan, showed that the leaf extract contained 26 compounds: Stigmast-4-en-3-one C29H48O, lupeol C30H50O, tetracontane C29H50O , Heptacosane C44H90, Vitamin E C29H56 , γ-TocopherolC29H50O2, 2H-1-benzopyran-6-ol C28H48O2 ,heptacosane C27H46O, Squalene C27H56 ,methyl [2] 5,11,14,17 eicosatetraenoate C30H501,2-Benzene dicarboxylic acid bisoctylester C24H38O4, Phenol-3 pentadecyl C21H36O,Octadecanoic acid C18H36O2,. 9,12-Octadecadienoylchloride[z,z] C18H31ClO. Phytol C20H40O, n-Hexadecanoic acid C16H32O2,3, 7, 11, 15-Tetramethyl-2-hexadecen-1-ol C20H40O. 3,7,11,15-tetramethyl-2-hexadecen-1-ol C20H40O,.5-Octadecene[E] C18H36, Tetradecanoic acid C14H28O2 , Decane -5,6-bis(2,2-dimethyl propylidene)(E,Z) C20H38,1-Hexadecene C16H32 .Cholestan-3-d-2- methylene(3β,5a)C28H48O, Benzocycloheptatriene C11H10, Benzene- 2-ethenyl-1,3,5-trimethyl C11H14 and Napthalene C10H8 . Most of these compounds have marked anticancer, anti-tumour and anti-inflammatory properties making the plant leaf a potent medicine for the treatment of cancer, tumour, inflammation and cardiovascular disease.
Keywords: anti-inflammation, anticancer., antimicrobials, antitumour, phytochemicals, spondias mombin
