Natural Products Chemistry: A Pathway for Drugs Discovery (Published)
Long before the era of high through-put screening and genomics, drug discovery relied heavily on natural products. Drug discovery involves the identification of New Chemical Entities (NCEs) of potential therapeutic value, which can be obtained through isolation from natural sources, through chemical synthesis or a combination of both. However, the success stories for the discoveries Penicillin from penecilium rubens, Paclitaxel yew tree and marketed as Taxol, Aspirin from Willow bark of Salix alba tree etc. have pave way for scholars in the field of natural product and organic chemistry to focus their research work in drug-derived from plants and microorganisms. Natural products derived from these sources are rich in bioactive compound, which have been use over years throughout human history and evolution as remedies for various ailments. This paper however, X-rayed the sources and classes of natural products, pharmaceuticals derived from Natural product, and uses of natural products. The paper also recommended among others that, government should fund research in the area of natural products, pharmaceutical chemistry and pharmacognocy.
Keywords: Chemistry, Drug, Microorganisms, Natural products, metabolism, plant
Locator Theory for Ele-Ments in Periodic Table “Lept” (Published)
The undermentioned theory is aimed to simplify the study of elements described in periodic table. The theory is formulated to ascertain the location of the elements as described in the periodic table without using the periodic table. The theory provides the simpler medium to find out the group number as well as period number which can be further utilized to study properties of elements.
Keywords: Chemistry, Group Number, Locator Theory, Period Number, Periodic Table
Green Chemistry: a Panacea for Environmental Sustainability Agriculture in Global Perspective (Published)
The environment is a very important component necessary for the existence of both man through agriculture. Agriculture is one of the oldest and global sources of human livelihood. Producing food, transportation, and energy for teeming population has led to large and widespread increases in the use of synthetic nitrogen (N) fertilizers and fossil fuel combustion, resulting in a leakage of N into the environment as various forms of air ,soil and water pollution. Information for the paper was through secondary data, in which principles of green chemistry, impact of pesticides and inorganic fertilizers were discussed with the confirmation of negative impacts through their applications in agriculture. Sustainable Agricultural Applications in Green Chemistry was discussed and bio-pesticides and bio-fertilizers were recommended as an alternative tools . Green Chemistry aims not only for safer products, less hazardous consequences to the environment, saving energy and water, but includes broader issues which can promote in the end Sustainable Development. The beginning of green chemistry is frequently considered as a response to the need to reduce the damage of the environment by man-made materials and the processes used to produce them.
Keywords: Agriculture, Chemistry, Environment, Green, Sustainability