Hacking the Blood-Brain Barrier (Published)
The undermentioned method focuses on temporarily disrupting the tight junctions between the endothelial cells that form the blood-brain barrier, as well as temporarily permeabilising the cell membrane of the endothelial cells and the cells in the target tissue and in doing so, facilitating drug uptake into the target tissue.
Keywords: Blood brain Barrier, Drug uptake, Microbubbles, Neurosciences, permeabilising the cell membrane