Evaluation of Innate Immune Response and Bacterial Isolates Rather Than M Tuberculosis in Tuberculosis Patient (Published)
This work was applied on 109 TB patients admitted to the Babylon center of tuberculosis and chest disease. Sputm cultures of tuberculosis patients reveals major types of bacteria , Streptococcus.pyogens, Staphylococci.aureus, Moraxella catarrhalis , Pseudomonads.aeruginosa, Neisseria.menengenitites Streptococcus.virdanse, Streptococcus.epidermidis Haemophilus.influenzae . and Serratia macescence
S. aureus form high rate of these isolates .
This study aims to evaluated the parameters of cell mediated immunity including IL6 and phagocytosis for tuberculosis patients.
Blood samples were collected from patients and controls groups to estimate phagocytosis, interleukin-6 (IL-6) by ELISA (Enzyme linked immunosorbant assay) method.The cell mediated investigation showing that there is a significantly increased (p< 0.05) in phagocytosis activity of neutrophils in TB patients (21%) compared to control group (11.85%) and significantly increased (p> 0.05) of IL-6 level in the TB patients (388.05 ) IU/ml compared to control group (82.83) IU/ml . The results was revealed that rural-urban ratio was higher in rural than in urban for TB patients , furthermore the T.B infection was higher in malr than femal.
Keywords: Bacterial Isolate, IL6, Phagocytosis, TB Patients