This research investigates the intricate relationship between sickle cell disease (SCD) and the ABO blood group system. The study was aim to achieve the primary objective which is to determine the prevalence of ABO blood group among sickle cell patients. A survey research design was adopted to address the research objective. The study focused on patients with sickle cell disease at Azare General Hospital, Katagum Local Government, Bauchi State of Nigeria. A total of 134 respondents (population) were randomly selected, using Taro Yamane’s Formula, the sample size (100) was determined. Data were collected through structured questionnaires, incorporating both primary and secondary sources, the collected data underwent analysis using frequency and percentage table. The findings have brought an insight on the prevalence of ABO blood group among sickle cell patients and the sickle cell disease. The research contributes positive information to the understanding of the interplay between sickle cell disease and the ABO blood group system. The results have implication for clinical management and further research in the field. The finding was the higher prevalence of (SCD) with blood group O.
Keywords: Sickle Cell Disease, and ABO Blood Group
