Mind Matters: Possible Links Between Gut–Microbiota with Psychiatric and Neurodegerative Disorders (Published)
Numerous health conditions, including neuropsychiatric disorders like Attention Deficit/Hyperactivity Disorder (ADHD) and neurodegenerative diseases like Parkinson’s Disease (PD), have been linked to the gut microbiome, a diverse community of microorganisms in the gastrointestinal tract. This review explores the gut-brain axis and how it affects the pathophysiology of Parkinson’s disease and ADHD. According to recent studies, the gut microbiota can affect various disorders by influencing immune system interactions, neurotransmitter regulation, and inflammatory responses. Changes in the makeup of the gut microbiota have been connected to behavioral symptoms in ADHD, suggesting a possible relationship between neurodevelopmental processes and gut health. It is believed that gut dysbiosis plays a role in Parkinson’s disease progression, with particular microbial patterns perhaps causing neuroinflammation and neuronal degeneration. This review summarizes the available data, investigates gut microbiome-targeting therapy approaches, and emphasizes the need for more study to fully understand the complex gut-brain connections and create microbiome-based treatments for PD, depression, anxiety, and ADHD.
Keywords: Anxiety, Attention Deficit Hyperactivity Disorder, Depression, Gut microbiome, Parkinson’s Disease